Fact-sheet: Glomus tumor


Updated on 02/18/2020 at 12:16 PM

Note : 0/10

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Definition

Benign tumor of the digital extremities: hamartoma arising from the glomus body, a neuromyoarterial receptor (a millimeter-sized organ involved in thermoregulation)

Accounts for 1.2% of hand tumors.
Small tumors (3 to 6 mm) whose diagnosis is often difficult.

Sex: female (60%).
Age: mean of 40 years (22-65 years).
Side: left+++

Locations:

  • 70% subungual
  • 20% pulp
  • 10% lateral pulp

Clinical features

Pain:+++

  • spontaneous: intense, sudden, lancinating
  • provoked by pressure over the lesion site
  • locoregional irradiation+++
  • limitation of functional activity

Physical findings:

  • Subungual glomus tumor: bluish or reddish discoloration, nail dystrophy
  • Pulp glomus tumor: budding swelling, indurated swelling, bluish discoloration

Associated signs:

  • Trophic disturbances such as digital hypotrophy
  • Vasomotor signs

Radiography

- Bone erosion of the distal phalanx
- May show regular scalloping or overlying soft tissue thickening

Ultrasound

  • Round hypoechoic or anechoic formation, with small internal cystic changes.
  • Doppler: marked hyperemia ++

CT

Useful for demonstrating atypical intravisceral locations: hypervascular nodule

MRI

  • T1: hypointense
  • T2: hyperintense
  • marked enhancement after Gadolinium injection as early as the arterial phase
  • Visibility of numerous perilesional vessels reflecting its hypervascularity

Management

  • Complete surgical excision
  • Diagnostic confirmation: pathology
  • Recurrence possible with a less typical appearance of glomus tumor.

Differential diagnosis

  • Ganglion cyst
  • Venous malformation
  • Soft tissue chondroma
  • Giant cell tumor
  • Epidermoïd cyst
  • Neuroma / Schwannoma
  • Subungual melanoma