Fact-sheet: Primary adrenal lymphoma


Updated on 03/26/2020 at 8:59 AM

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Definition

Malignant tumor of the spleen arising from lymphocytic cells.

Population affected: young and immunocompromised patients.

Clinical features

Fever, weight loss, malaise, sweats, splenomegaly

Ultrasound

Homogeneous, hypoechoic splenomegaly.

CT

- Hypodense nodular lesions (10-20 HU)
- Very faint enhancement after contrast injection
- Splenic hilar and/or retroperitoneal lymphadenopathy.

Management

Chemotherapy and radiation therapy.
Surgical resection in cases of isolated splenic lesion.

Differential diagnosis

Splenic metastases.