Fact-sheet: Basal cell carcinoma


Updated on 09/27/2024 at 9:22 AM

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Definition

Malignant, epithelial skin tumor arising from basal cells of the epidermis.

Clinical features

Most common skin tumor, especially in elderly patients and in sun-exposed areas.

Loco-regional progression that can be highly invasive and destructive to adjacent structures.

Pulmonary and bone metastatic spread is exceptional.

6 clinical forms: nodular, cystic, ulcerated, superficial, sclerodermiform, and pigmented and/or keratotic variants.

Generally no imaging, except in locally advanced or periorificial forms.

MRI

In locally advanced or periorificial forms.

Objectives:

  • Identify clinically occult involvement
  • Decide on possible neoadjuvant treatment
  • Plan complete surgical excision.

Difficult to visualize on MRI:

  • ulceration, tissue loss, very thin lesion
  • minimal T2 hyperintensity, faint enhancement
  • value of the T1 sequence+++, the lesion appearing hypointense relative to the underlying hypodermis

Useful in post-treatment follow-up to detect subclinical recurrence

Management

Superficial, non-periorificial forms: medical treatment.

Other forms: surgical treatment with slow-Mohs analysis for difficult locations or infiltrative forms.