Fact-sheet: Anterior interosseous nerve syndrome
  • Kiloh-Nevin syndrome


Updated on 04/18/2018 at 4:23 PM

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Definition

Denervation in the territory of the anterior interosseous nerve, affecting:

- the flexor pollicis longus muscle

- the pronator quadratus muscle

- the flexor digitorum profundus muscle

Etiologies: Most often idiopathic, but may be traumatic, related to extrinsic nerve compression, or, more rarely, secondary to an intrinsic nerve lesion (tumoral)

Clinical features

Motor deficit of the muscles involved:

  • Inability to perform the 'OK' sign with flexion of the thumb and index finger interphalangeal joints
  • Impaired elbow pronation and flexion

MRI

Reference examination.

Denervation edema, hyperintense on STIR:

- flexor pollicis longus muscle

- pronator quadratus muscle

- flexor digitorum profundus muscle

In the long term, amyotrophy and fatty involution, assessed on T1-weighted imaging.

Search for an underlying etiology

Differential diagnosis

Other nerve entrapment syndromes:

pronator teres syndrome, carpal tunnel syndrome