Fact-sheet: Solitary bone cyst
Updated on 10/03/2018 at 9:30 AM
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Definition
Essential bone cyst = solitary bone cyst
Cystic bone dystrophy of unknown origin
Pseudotumoral lesion, metaphyseal bone cavity filled with clear citrine-yellow fluid
Course:
- Arises adjacent to the physis and enlarges during the growth period, extends toward the diaphysis while remaining in contact with the physis: local extension
- Latent in adulthood, migrates away from the physis with spontaneous regression over several years
- Does not undergo malignant transformation
Clinical features
Epidemiology: most common benign bone tumor of the appendicular skeleton in children
3% of all primary bone tumors
90% of cases are diagnosed during the first 2 decades of life, exceptional after age 30
Male predominance 2M/1F
Location: Proximal metaphysis of long bones - humerus 50%, femur 25%, proximal or distal tibia.
Calcaneus and talus in elderly patients
Rare in the spine, pelvis, skull, and facial bones
Average size: 6-8 cm
Presentation: Pain if fracture or fissure
Fracture occurs in 2/3 of cases
Otherwise asymptomatic, incidental discovery
Radiography
Radiographs alone are sufficient for diagnosis:
- Ovoid lucency centered in the metaphyseal region, abutting the growth plate
- Well-defined, sharply demarcated margins
- Thinned but intact cortex
- Dense rim on the diaphyseal aspect: "fallen fragment" cup sign
- Fracture: periosteal reaction, fallen fragment sign (bone fragment settling at the bottom of the cavity)
CT
if diagnostic uncertainty:
-well-defined lytic lesion, fluid-filled.
MRI
if diagnostic uncertainty:
-well-defined lytic lesion of fluid signal, T1 hypointense, T2 hyperintense, without contrast enhancement
Management
- Typical appearance: no biopsy required
- Pathologic fracture: orthopedic management, normal healing time
- Osteosynthesis and bone grafting
- Radiologic follow-up until the end of growth
Differential diagnosis
Aneurysmal bone cyst:
- 10-30 years
- Long and flat bones: pelvis, posterior spinal elements, lower limb
- Expansile lytic lesion composed of multiple blood-filled cavities separated by septa of variable thickness, soap-bubble appearance
- Eccentric and highly expansile
Chondromyxoid fibroma:
- Male, 10-30 years, main location: knee
- Mixed cartilaginous and myxoid composition
- Geographic osteolysis, dense rim, thick bony septum