Fact-sheet: Constrictive pericarditis


Updated on 07/19/2022 at 6:27 PM

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Definition

Constrictive pericarditis is a type of pericarditis characterized by fibrous or calcified thickening of the pericardium, leading to diastolic dysfunction and potentially right heart failure.

Clinical features

Increased diastolic pressure in all 4 cardiac chambers --> Restrictive physiology --> Symptoms of global heart failure with right-sided predominance: dyspnea, orthopnea, exertional fatigue, hepatomegaly, ascites, jugular venous distension.

Radiography

Pericardial calcifications (visible in 50% of cases)

Ultrasound

Echocardiography:

- Pericardial thickening +/- pericardial effusion

- Exaggerated ventricular interdependence and intrathoracic-intracardiac dissociation

- Exaggerated respirophasic septal shift with characteristic "shudder" sign

CT

Highly sensitive for detecting pericardial calcifications

Pericardial thickening > 4mm (not sufficient alone to establish the diagnosis)

After injection: septal flattening, reflux of contrast into the inferior vena cava and dilated hepatic veins

MRI

Better than CT for differentiating pericardial thickening from pericardial effusion

Cardiac cine-MRI: septal flattening and septal bounce

Differential diagnosis

Pericarditis

Restrictive cardiomyopathy