Fact-sheet: Juvenile papillomatosis
Updated on 10/03/2019 at 4:23 PM
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Definition
Rare, affects women under 20 years of age in 69% of cases.
- Corresponds to a benign papillary proliferation developing within the ducts
- Risk of degeneration in cases of associated hyperplasia
- Concurrent association with adenocarcinoma in approximately 10% of cases
Clinical features
- Unilateral breast mass of recent onset
- Firm, smooth or lobulated, mobile mass
- Usually located in the upper outer quadrants
- Occasionally painful
- Possible nipple discharge
Radiography
Mammography:
- Dense breasts
- Ill-defined, sometimes spiculated opacity
- Microcalcifications: polymorphic, punctate, regular, coarsely rounded or irregular, even vermicular. They are scattered or in focal clusters
Ultrasound
First-line in young patients
- Solid mass with an irregular hypoechoic peripheral area containing clustered cysts
- Occasional microcalcifications within the cysts
Management
Complete excision (wide segmentectomy) of the mass to avoid recurrence and not miss an associated cancer
Annual clinical follow-up, mammography and ultrasound if clinical abnormality, atypia on pathology, or family risk factor for breast cancer