Fact-sheet: Osteoblastoma
Updated on 04/18/2018 at 4:14 PM
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Definition
Uncommon benign tumor closely related to osteoid osteoma (>2 cm).
Adolescents and young adults.
Involvement of the spine (posterior elements ++), long bones (diaphysis ++), hands and feet, flat bones, and skull bones.
Cortical, cancellous, or subperiosteal location.
Clinical features
Mild to moderate pain with slight nocturnal predominance (less pronounced symptomatology than osteoid osteoma).
Occasional nerve compression depending on location.
CT
Well-defined osteolytic area with peripheral sclerosis.
Intralesional calcifications.
Bone expansion, occasionally with cortical breakthrough and periosteal reaction.
MRI
Hypo- or isointense on T1.
Iso- or hyperintense on T2.
Enhancement after gadolinium injection.
Adjacent bone and soft tissue edema.
Nuclear medicine
Intense uptake on scintigraphy.
Differential diagnosis
Osteoid osteoma
Osteosarcoma
Aneurysmal bone cyst