Fact-sheet: Merkel-cell carcinoma
Updated on 09/27/2024 at 9:03 AM
Note : 0/10
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Definition
Cutaneous tumor of neuroendocrine origin associated with the presence of a polyomavirus in 80% of cases, with a poor prognosis (comparable to that of Malignant melanoma).
Clinical features
Exceptional tumor before age 50, with increasing incidence in immunocompromised patients (transplant, autoimmune disease, hematologic malignancy, HIV).
Predominance in sun-exposed areas with fair skin type.
Rapidly evolving exophytic red or flesh-colored cutaneous nodule, or subcutaneous nodule.
Ultrasound
Ultrasound of the primary region and draining lymph node areas
MRI
Staging workup with brain MRI
Nuclear medicine
Staging workup with 18-FDG PET-CT
