Fact-sheet: Hamartoma of breast


Updated on 06/30/2020 at 8:36 AM

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Definition

Benign breast lesion composed of adenolipomatous tissue, delineated by a capsule.

Clinical features

  • Asymptomatic
  • Palpable, firm

Radiography

  • Mass generally larger than 3 cm
  • Well circumscribed
  • Density with heterogeneous central areas related to the fat component (radiopaque and radiolucent areas)
  • Capsule
  • Halo sign: peripheral radiolucent zone caused by compression of surrounding tissue
  • May contain calcifications

Ultrasound

  • Well-circumscribed formation
  • Heterogeneous structure with hypoechoic and hyperechoic areas/bands

MRI

  • Breast-within-a-breast appearance
  • Fat and matrix tissue with variable enhancement

Management

The presence of fibroglandular tissue makes it possible for carcinoma to develop within the hamartoma.

Differential diagnosis

  • Liposarcoma
  • Cowden disease
  • Lipoma
  • Fibroadenoma