Fact-sheet: Wegener granulomatosis


Updated on 07/14/2016 at 10:29 AM

Note : 10/10 ( 1 note )

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Definition

Necrotizing vasculitis of small-caliber vessels with ANCA, combining vascular wall inflammation and peri- and extravascular granulomatosis

Clinical features

Multiple mononeuropathy +++.
Sinusitis.
Renal involvement

CT

Pulmonary involvement:
- Nodules, granulomas, cavitated necrotic masses
- Frequent involvement of the trachea and large bronchi.
- Possible tracheal or bronchial stenosis.
- Occasionally, ulcerations, pseudotumors.