Fact-sheet: Panacinar emphysema


Updated on 07/01/2020 at 8:58 AM

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Definition

Panacinar emphysema involves all portions of the acinus and secondary pulmonary lobule more or less uniformly.

It predominates in the lower lobes and is a form of emphysema associated with alpha-1 antitrypsine deficiency.

CT

Presents as a generalized reduction in pulmonary parenchyma with decreased caliber of blood vessels in the affected areas.

It can coexist with and be intermixed with severe centrilobular emphysema.