Fact-sheet: Gadoliuium deposition in the brain


Updated on 06/29/2020 at 10:55 AM

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Definition

Residual gadolinium accumulation in the brain in patients who have undergone numerous contrast-enhanced MRIs.

Proposed mechanism:
passage into the CSF via the choroid plexus
and release of a few atoms depending on the instability of the contrast agent (linear chelates ++)

At-risk populations: children and patients with chronic disease (MS, IBD)

Clinical features

Currently unknown

CT

No abnormality

MRI

Spontaneous T1 hyperintensities of:

  • dentate nuclei of the cerebellum
  • basal ganglia: globus pallidus of the lentiform nuclei